Anti-E2F4 antibody
Product Name Anti-E2F4 antibody
Catalog No PAab02602
Packing 100ug
Form liquid
Alternative Name
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Immunogen E2F transcription factor 4, p107/p130-binding
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC,IP
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human lymphoma usingE2F4 antibody at dilution of 1:100
WB use
A431 cells were subjected to SDS PAGE followed by western blot with PAab02602(E2F4 antibody) at dilution of 1:1000
Protein Information
Gene ID1874
Uniprot ID Q16254
Calculated MW
location