Anti-ENPP1 antibody

$275.00

  • Model: PAab02773
  • 50 Units in Stock
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Anti-ENPP1 antibody

Product Name Anti-ENPP1 antibody

Catalog No PAab02773

Packing 100ug

Form liquid

Alternative Name M6S1 antibody, NPPS antibody, PC1 antibody, PDNP1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

Immunogen ectonucleotide pyrophosphatase/phosphodiesterase 1

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID5167

Uniprot ID P22413

Calculated MW

location

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