Anti-HDAC4 antibody

$275.00

  • Model: LSMab09984
  • 100 Units in Stock
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Anti-HDAC4 antibody

Product Information
Catalog No.:    LSMab09984
Size:    100μg
Form:    liquid
Purification:    Immunogen affinity purified
Purity:    ≥95% as determined by SDS-PAGE
Host:    Rabbit
IsoType:    IgG
Storage:    PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Immunogen information
Immunogen:    histone deacetylase 4
Synonyms:    KIAA0288
Calculated MW:    130 kDa
Uniprot ID :    P56524

Application
Specificity:    Human, Mouse; other species are not tested. Please decide the specificity by homology
Tested Application:    ELISA, WB
Recommended dilution:    WB: 1:500 - 1:2000

Validation :

 

HeLa cells were subjected to SDS PAGE followed by western blot with LSMab09984(HDAC4 antibody) at dilution of 1:1000


 

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