Anti-ICOS antibody
Product Name Anti-ICOS antibody
Catalog No PAab04110
Packing 100ug
Form liquid
Alternative Name AILIM
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
Immunogen inducible T-cell co-stimulator
Specificity Human
Tested Application ELISA,WB
Recommended dilution
IHC use
WB use
Protein Information
Gene ID29851
Uniprot ID Q9Y6W8
Calculated MW
location