Anti-Lin28B-specific antibody

Product Name Anti-Lin28B-specific antibody

Catalog No PAab04786

Packing 100ug

Form liquid

Alternative Name CSDD2 antibody, FLJ16517 antibody, lin 28 homolog B (C. elegans) antibody, Lin 28B antibody, Lin28 antibody, LIN28B antibody, Protein lin 28 homolog B

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.

Immunogen lin-28 homolog B (C. elegans)

Specificity Human, Mouse

Tested Application ELISA,IHC,IF,WB

Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100

IHC use

Immunohistochemistry of paraffin-embedded human spleen usingLin28B-specific antibody at dilution of 1:50

WB use

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab04786( Lin28B-specific Antibody) at dilution of 1:1000

Protein Information

Gene ID389421

Uniprot ID Q6ZN17

Calculated MW 28kDa

location