Anti-MICALL2 antibody

Product Name Anti-MICALL2 antibody

Catalog No PAab05179

Packing 100ug

Form liquid

Alternative Name JRAB

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).

Immunogen MICAL-like 2

Specificity Human

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID79778

Uniprot ID Q8IY33

Calculated MW

location