Anti-MX1 antibody

$275.00

  • Model: LSMab09996
  • 100 Units in Stock
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Anti-MX1 antibody

Product Information
Catalog No.:    LSMab09996
Size:    100μg
Form:    liquid
Purification:    Immunogen affinity purified
Purity:    ≥95% as determined by SDS-PAGE
Host:    Rabbit
IsoType:    IgG
Storage:    PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Immunogen information
Immunogen:    Myxovirus resistance protein 1
Synonyms:    IFI 78K, IFI78, Interferon induced protein p78, MX, MX1, MxA, Myxovirus resistance protein 1
Calculated MW:    76 kDa
Uniprot ID :    P20591

Application
Specificity:    Human, rat; other species are not tested. Please decide the specificity by homology
Tested Application:    ELISA, WB, IHC
Recommended dilution:    WB: 1:500-1:2000; IHC: 1:20-1:200

Validation :

     


Immunohistochemistry of paraffin-embedded rat kidney slide using LSMab09996(MX1 Antibody) at dilution of 1:100
 

HeLa cells were subjected to SDS PAGE followed by western blot with LSMab09996(MX1 antibody) at dilution of 1:1000

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