Anti-NSUN2 antibody

Product Name Anti-NSUN2 antibody

Catalog No PAab05870

Packing 100ug

Form liquid

Alternative Name SAKI antibody, TRM4

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Immunogen NOL1/NOP2/Sun domain family, member 2

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using NSUN2 Antibody at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA bufferpH9).

WB use

Protein Information

Gene ID54888

Uniprot ID Q08J23

Calculated MW

location