Anti-NUMB antibody
Product Name Anti-NUMB antibody
Catalog No PAab05914
Packing 100ug
Form liquid
Alternative Name
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Immunogen numb homolog (Drosophila)
Specificity Human, Mouse
Tested Application ELISA,WB,IHC,IF,FC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human brain usingNUMB antibody at dilution of 1:100
WB use
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab05914(NUMB antibody) at dilution of 1:800
Protein Information
Gene ID8650
Uniprot ID P49757
Calculated MW
location