Anti-Nurr1/NR4A2 antibody


  • Model: PAab05936
  • 50 Units in Stock
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Anti-Nurr1/NR4A2 antibody


Product Name Anti-Nurr1/NR4A2 antibody

Catalog No PAab05936

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

NR4A2 belongs to the orphan nuclear receptor (NR) family referred to as NR4A family, which have been implicated in cell cycle regulation, apoptosis, inflammation, metabolism and more recently in carcinogenesis [PMID:22583411]. NR4A2 also has a role in the expression of several proteins that are necessary for the synthesis and regulation of dopamine (DA), such as tyrosine hidroxilase, dopamine transporter, vesicular monoamine transporter 2, and cRET [PMID:22294735]. Act as a transcriptional regulator, NR4A2 is essential for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons [PMID: 17184956].

Immunogen nuclear receptor subfamily 4, group A, member 2

Specificity Human

Tested Application ELISA,IHC

Recommended dilution  WB : 1:500-1:1000 IHC : 1:50-1:500 IF : 1:50-1:500

IHC use

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using Anti-Nurr1/NR4A2 antibody at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

WB use

fetal human brain tissue were subjected to SDS PAGE followed by western blot with Anti-Nurr1/NR4A2 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours

Protein Information

Gene ID4929

Uniprot ID

Calculated MW 66 kDa


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