Anti-PTGES3 antibody

Product Name Anti-PTGES3 antibody

Catalog No PAab06918

Packing 100ug

Form liquid

Alternative Name P23 antibody, TEBP

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

Immunogen prostaglandin E synthase 3 (cytosolic)

Specificity Human,Mouse ,Rat

Tested Application ELISA,IF,IP,WB,FC

Recommended dilution

IHC use

WB use

Protein Information

Gene ID10728

Uniprot ID Q15185

Calculated MW

location