Anti-RECQL5 antibody

$275.00

  • Model: PAab07227
  • 50 Units in Stock
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Anti-RECQL5 antibody

Product Name Anti-RECQL5 antibody

Catalog No PAab07227

Packing 100ug

Form liquid

Alternative Name RECQ5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.

Immunogen RecQ protein-like 5

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human pancreas cancer usingRECQL5 antibody at dilution of 1:50

WB use

mouse testis tissue were subjected to SDS PAGE followed by western blot with PAab07227(RECQL5 antibody) at dilution of 1:1000

Protein Information

Gene ID9400

Uniprot ID O94762

Calculated MW

location

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