Anti-RENALASE antibody


  • Model: PAab07238
  • 50 Units in Stock
Ask a question

Add to Cart:

Anti-RENALASE antibody

Product Name Anti-RENALASE antibody

Catalog No PAab07238

Packing 100ug

Form liquid

Alternative Name C10orf59 antibody, MAO C antibody, Monoamine oxidase C antibody, RENALASE antibody, RNLS

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity. (PMID:15841207 ) This antibody is specific to RNLS.

Immunogen chromosome 10 open reading frame 59

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000

IHC use

Immunohistochemistry of paraffin-embedded human kidney usingRENALASE antibody at dilution of 1:100

WB use

human heart tissue were subjected to SDS PAGE followed by western blot with PAab07238(RENALASE antibody) at dilution of 1:500

Protein Information

Gene ID55328

Uniprot ID Q5VYX0

Calculated MW 35kDa


No customer comments for the moment.

Add A Comment

Related Products


No products

Total $0.00

Prices don't include postage.