Anti-SOD1 antibody

$275.00

  • Model: LSMab09989
  • 100 Units in Stock
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Anti-SOD1 antibody

Product Information
Catalog No.:    LSMab09989
Size:    100μg
Form:    liquid
Purification:    Immunogen affinity purified
Purity:    ≥95% as determined by SDS-PAGE
Host:    Rabbit
IsoType:    IgG
Storage:    PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

Immunogen information
Immunogen:    superoxide dismutase 1, soluble
Synonyms:    Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,
hSod1
Calculated MW:    16 kDa
Uniprot ID :    P00441

Application
Specificity:    Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology
Tested Application:    ELISA, WB, IHC
Recommended dilution:    WB: 1:500-1:2000; IHC: 1:50-1:500

Validation :

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using LSMab09989(SOD1 Antibody) at dilution of 1:200
 

HEK-293 cells were subjected to SDS PAGE followed by western blot with LSMab09989(SOD1 antibody) at dilution of 1:1000

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