Anti-VPS53 antibody

$275.00

  • Model: PAab09448
  • 50 Units in Stock
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Anti-VPS53 antibody

Product Name Anti-VPS53 antibody

Catalog No PAab09448

Packing 100ug

Form liquid

Alternative Name FLJ10979 antibody, HCCS1 antibody, hVps53L antibody, pp13624 antibody, VPS53

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Immunogen vacuolar protein sorting 53 homolog (S. cerevisiae)

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB :1:500-1:5000

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