Anti-VPS8 antibody

$275.00

  • Model: PAab09451
  • 50 Units in Stock
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Anti-VPS8 antibody

Product Name Anti-VPS8 antibody

Catalog No PAab09451

Packing 100ug

Form liquid

Alternative Name FLJ32099 antibody, KIAA0804 antibody, VPS8

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290).

Immunogen vacuolar protein sorting 8 homolog (S. cerevisiae)

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IF

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