Anti-WDR24 antibody

$300.00

  • Model: PAab09488
  • 50 Units in Stock
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Anti-WDR24 antibody

Product Name Anti-WDR24 antibody

Catalog No PAab09488

Packing 100ug

Form liquid

Alternative Name C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, WD repeat domain 24 antibody, WDR24

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2 (PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).

Immunogen WD repeat domain 24

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF

Recommended dilution WB : 1:500-1:5000;IP:1:200-1:2000;IF:1:10-1:100;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human ovary usingWDR24 antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09488(WDR24 antibody) at dilution of 1:500

Protein Information

Gene ID84219

Uniprot ID Q96S15

Calculated MW 102kDa

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