Anti-WRAP53 antibody

$275.00

  • Model: PAab09523
  • 50 Units in Stock
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Anti-WRAP53 antibody

Product Name Anti-WRAP53 antibody

Catalog No PAab09523

Packing 100ug

Form liquid

Alternative Name FLJ10385 antibody, TCAB1 antibody, WDR79 antibody, WRAP53

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.

Immunogen WD repeat containing, antisense to TP53

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:1000

IHC use

Immunohistochemistry of paraffin-embedded human testis usingWRAP53 antibody at dilution of 1:100

WB use

human kidney tissue were subjected to SDS PAGE followed by western blot with PAab09523(WRAP53 antibody) at dilution of 1:300

Protein Information

Gene ID55135

Uniprot ID Q9BUR4

Calculated MW 59kDa,Observed 72kDa

location

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