Anti-WT1 antibody

Product Name Anti-WT1 antibody

Catalog No PAab09528

Packing 100ug

Form liquid

Alternative Name GUD antibody, WAGR antibody, Wilms tumor 1 antibody, Wilms tumor protein antibody, WIT 2 antibody, WT1 antibody, WT33

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Immunogen Wilms tumor 1

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IP

Recommended dilution WB:1:500-1:5000;IP:1:500-1:5000

IHC use

WB use

human kidney tissue were subjected to SDS PAGE followed by western blot with PAab09528(WT1 antibody) at dilution of 1:300

Protein Information

Gene ID7490

Uniprot ID P19544

Calculated MW 49kDa,Observed 33kDa,55kDa

location