Anti-XPO7 antibody

$245.00

  • Model: PAab09551
  • 50 Units in Stock
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Anti-XPO7 antibody

Product Name Anti-XPO7 antibody

Catalog No PAab09551

Packing 100ug

Form liquid

Alternative Name Exp7 antibody, exportin 7 antibody, KIAA0745 antibody, Ran binding protein 16 antibody, RANBP16 antibody, XPO7

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

Immunogen exportin 7

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB:1:500-1:5000

IHC use

WB use

K-562 cells were subjected to SDS PAGE followed by western blot with PAab09551(XPO7 antibody) at dilution of 1:300

Protein Information

Gene ID23039

Uniprot ID Q9UIA9

Calculated MW 124kDa,Observed 100kDa

location

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