Anti-XRCC2 antibody


  • Model: PAab09553
  • 50 Units in Stock
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Anti-XRCC2 antibody

Product Name Anti-XRCC2 antibody

Catalog No PAab09553

Packing 100ug

Form liquid

Alternative Name DKFZp781P0919 antibody, DNA repair protein XRCC2 antibody, XRCC2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2- dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.

Immunogen X-ray repair complementing defective repair in Chinese hamster cells 2

Specificity Human

Tested Application ELISA,WB

Recommended dilution WB:1:200-1:2000;IP:1:200-1:2000

IHC use

WB use

K-562 cells were subjected to SDS PAGE followed by western blot with PAab09553( XRCC2 Antibody) at dilution of 1:600

Protein Information

Gene ID7516

Uniprot ID O43543

Calculated MW 32kDa,Observed 40kDa


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