Anti-XRCC4 antibody

$245.00

  • Model: PAab09554
  • 50 Units in Stock
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Anti-XRCC4 antibody

Product Name Anti-XRCC4 antibody

Catalog No PAab09554

Packing 100ug

Form liquid

Alternative Name DNA repair protein XRCC4 antibody, XRCC4

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Immunogen X-ray repair complementing defective repair in Chinese hamster cells 4

Specificity Human,Rat

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB:1:1000-1:10000;IHC:1:20-1:200;IP:1:200-1:2000

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer usingXRCC4 antibody at dilution of 1:100

WB use

K-562 cells were subjected to SDS PAGE followed by western blot with PAab09554(XRCC4 antibody) at dilution of 1:1000

Protein Information

Gene ID7518

Uniprot ID Q13426

Calculated MW 38kDa,Observed 55kDa

location

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