Anti-XRN1 antibody


  • Model: PAab09556
  • 50 Units in Stock
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Anti-XRN1 antibody

Product Name Anti-XRN1 antibody

Catalog No PAab09556

Packing 100ug

Form liquid

Alternative Name 5 3 exoribonuclease 1 antibody, 5' 3' exoribonuclease 1 antibody, DKFZp434P0721 antibody, DKFZp686B22225 antibody, DKFZp686F19113 antibody, FLJ41903 antibody, SEP1 antibody, XRN1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Immunogen 5'-3' exoribonuclease 1

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF

Recommended dilution WB:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human heart slide using XRN1 Antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09556(XRN1 antibody) at dilution of 1:600

Protein Information

Gene ID54464

Uniprot ID Q8IZH2

Calculated MW 192kDa


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