Anti-XRN2 antibody

$275.00

  • Model: PAab09557
  • 50 Units in Stock
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Anti-XRN2 antibody

Product Name Anti-XRN2 antibody

Catalog No PAab09557

Packing 100ug

Form liquid

Alternative Name XRN2 antibody, DHM1 like protein antibody, DHP protein antibody, 5' 3' exoribonuclease 2 antibody, 5 3 exoribonuclease 2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).

Immunogen 5'-3' exoribonuclease 2

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB:1:200-1:1000

IHC use

WB use

HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09557(XRN2 antibody) at dilution of 1:200

Protein Information

Gene ID22803

Uniprot ID Q9H0D6

Calculated MW 100kDa,Observed 100kDa,55kDa

location

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