Anti-YBX1 antibody

$300.00

  • Model: PAab09561
  • 50 Units in Stock
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Anti-YBX1 antibody

Product Name Anti-YBX1 antibody

Catalog No PAab09561

Packing 100ug

Form liquid

Alternative Name BP 8 antibody, CBF A antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, DNA binding protein B antibody, EFI A antibody, Enhancer factor I subunit A antibody, MDR NF1 antibody, NSEP 1 antibody, NSEP1 antibody, Y box binding protein 1 antibody, Y box transcription factor antibody, YB 1 antibody, YB1 antibody, YBX1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.

Immunogen Y box binding protein 1

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IP,IF

Recommended dilution WB:1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human placenta usingYBX1 antibody at dilution of 1:100

WB use

MCF7 cells were subjected to SDS PAGE followed by western blot with PAab09561(YBX1 antibody) at dilution of 1:500

Protein Information

Gene ID4904

Uniprot ID P67809

Calculated MW 36kDa,Observed 50kDa

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