Anti-YTHDF1 antibody

$275.00

  • Model: PAab09572
  • 50 Units in Stock
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Anti-YTHDF1 antibody

Product Name Anti-YTHDF1 antibody

Catalog No PAab09572

Packing 100ug

Form liquid

Alternative Name C20orf21 antibody, DACA 1 antibody, FLJ20391 antibody, YTH domain family protein 1 antibody, YTH domain family antibody, member 1 antibody, YTHDF1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A- containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).

Immunogen YTH domain family, member 1

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB:1:500-1:5000;IP:1:500-1:5000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human brain usingYTHDF1 antibody at dilution of 1:100

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09572(YTHDF1 antibody) at dilution of 1:500

Protein Information

Gene ID54915

Uniprot ID Q9BYJ9

Calculated MW 61kDa

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