Anti-YWHAB antibody


  • Model: PAab09575
  • 50 Units in Stock
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Anti-YWHAB antibody

Product Name Anti-YWHAB antibody

Catalog No PAab09575

Packing 100ug

Form liquid

Alternative Name 14 3 3 antibody, 14 3 3 alpha antibody, 14 3 3 protein beta/alpha antibody, YWHAB

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Immunogen tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Specificity Human,Mouse ,Rat

Tested Application ELISA,IHC

Recommended dilution IHC:1:20-1:200

IHC use

Immunohistochemical of paraffin-embedded human colon cancer usingYWHAB antibody at dilution of 1:50

WB use

Protein Information

Gene ID7529

Uniprot ID P31946

Calculated MW 28kDa


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