Anti-ZBTB38 antibody


  • Model: PAab09593
  • 50 Units in Stock
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Anti-ZBTB38 antibody

Product Name Anti-ZBTB38 antibody

Catalog No PAab09593

Packing 100ug

Form liquid

Alternative Name ZBTB38 antibody, FLJ31131 antibody, FLJ35036 antibody, CIBZ antibody, FLJ22332

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl- CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA- replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).

Immunogen zinc finger and BTB domain containing 38

Specificity Human

Tested Application ELISA,WB,IHC

Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human testis usingZBTB38 antibody at dilution of 1:50

WB use

HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09593(ZBTB38 antibody) at dilution of 1:1000

Protein Information

Gene ID253461

Uniprot ID Q8NAP3

Calculated MW 134kDa


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