Anti-ZC3HC1 antibody

$275.00

  • Model: PAab09608
  • 50 Units in Stock
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Anti-ZC3HC1 antibody

Product Name Anti-ZC3HC1 antibody

Catalog No PAab09608

Packing 100ug

Form liquid

Alternative Name ZC3HC1 antibody, 1110054L24Rik antibody, hNIPA antibody, HSPC216 antibody, NIPA

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Immunogen zinc finger, C3HC-type containing 1

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB : 1:200-1:2000

IHC use

WB use

mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab09608(ZC3HC1 antibody) at dilution of 1:500

Protein Information

Gene ID51530

Uniprot ID Q86WB0

Calculated MW 55kDa

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