Anti-ZFP36L2 antibody

$275.00

  • Model: PAab09625
  • 50 Units in Stock
Ask a question


Add to Cart:

Anti-ZFP36L2 antibody

Product Name Anti-ZFP36L2 antibody

Catalog No PAab09625

Packing 100ug

Form liquid

Alternative Name BRF2 antibody, Butyrate response factor 2 antibody, EGF response factor 2 antibody, ERF 2 antibody, ERF2 antibody, Protein TIS11D antibody, RNF162C antibody, TIS11D antibody, ZFP36L2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation (By similarity).

Immunogen zinc finger protein 36, C3H type-like 2

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB : 1:200-1:2000

IHC use

WB use

HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09625(ZFP36L2 antibody) at dilution of 1:500

Protein Information

Gene ID678

Uniprot ID P47974

Calculated MW 51kDa

location

No customer comments for the moment.

Add A Comment

Related Products

Cart  

No products

Total $0.00

Prices don't include postage.

Cart