Anti-ZFYVE19 antibody

$300.00

  • Model: PAab09629
  • 50 Units in Stock
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Anti-ZFYVE19 antibody

Product Name Anti-ZFYVE19 antibody

Catalog No PAab09629

Packing 100ug

Form liquid

Alternative Name FLJ14840 antibody, MPFYVE antibody, ZFYVE19

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Immunogen zinc finger, FYVE domain containing 19

Specificity Human

Tested Application ELISA,WB,IHC

Recommended dilution WB : 1:1000-1:10000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human heart slide using ZFYVE19 Antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09629(ZFYVE19 antibody) at dilution of 1:2000

Protein Information

Gene ID84936

Uniprot ID Q96K21

Calculated MW 52kDa

location

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