Anti-ZGPAT antibody

$300.00

  • Model: PAab09634
  • 50 Units in Stock
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Anti-ZGPAT antibody

Product Name Anti-ZGPAT antibody

Catalog No PAab09634

Packing 100ug

Form liquid

Alternative Name ZGPAT antibody, ZC3HDC9 antibody, ZC3H9 antibody, KIAA1847 antibody, GPATCH6

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Immunogen zinc finger, CCCH-type with G patch domain

Specificity Human, Mouse

Tested Application ELISA,WB

Recommended dilution WB : 1:500-1:5000

IHC use

WB use

L02 cells were subjected to SDS PAGE followed by western blot with PAab09634(ZGPAT antibody) at dilution of 1:1000

Protein Information

Gene ID84619

Uniprot ID Q8N5A5

Calculated MW 57kDa

location

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