Anti-ZIPK-Phospho 311Ser antibody

$275.00

  • Model: PAab09644
  • 50 Units in Stock
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Anti-ZIPK-Phospho 311Ser antibody

Product Name Anti-ZIPK-Phospho 311Ser antibody

Catalog No PAab09644

Packing 100ug

Form liquid

Alternative Name DAP kinase 3 antibody, DAP like kinase antibody, DAPK3 antibody, Dlk antibody, FLJ36473 antibody, ZIP antibody, ZIP kinase antibody, ZIPK

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

DAPK3(Death-associated protein kinase 3) is also named as ZIPK(Zipper-interacting protein kinase),Dlk(DAP-like kinase). It is a member of the death-associated protein kinase family associated with apoptosis in nonmuscle cells where it phosphorylates myosin regulatory light chain (RLC) to promote membrane blebbing. DAPK3 mRNA and protein are abundant in heart tissue and isolated ventricular neonatal rat cardiac myocytes(PMID:20038585). It has 2 isoforms produced by alternative splicing,named as ZIPK-L and ZIPK-S. This antibody is specific to ZIPK-Phospho 311Ser.

Immunogen death-associated protein kinase 3

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB : 1:500-1:5000;IP:1:200-1:1000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer usingZIPK-Phospho 311Ser antibody at dilution of 1:50

WB use

HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09644(ZIPK-Phospho 311Ser antibody) at dilution of 1:1000

Protein Information

Gene ID1613

Uniprot ID O43293

Calculated MW 53kDa

location

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