Anti-ZNF238 antibody

Product Name Anti-ZNF238 antibody

Catalog No PAab09671

Packing 100ug

Form liquid

Alternative Name 58 kDa repressor protein antibody, C2H2 171 antibody, RP58 antibody, TAZ 1 antibody, TAZ1 antibody, Transcriptional repressor RP58 antibody, ZBTB18 antibody, ZFP238 antibody, zinc finger protein 238 antibody, Zinc finger protein C2H2 171 antibody, ZNF238

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60-kDa band which corresponds to the full length of RP58 protein. In addition, a 48-kDa band, thought to be the truncated form 2 is detected (PMID: 9756912).

Immunogen zinc finger protein 238

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IP,IHC

Recommended dilution WB : 1:500-1:5000;IP:1:500-1:5000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using ZNF238 Antibody at dilution of 1:50

WB use

mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab09671(ZNF238 antibody) at dilution of 1:1000

Protein Information

Gene ID10472

Uniprot ID Q99592

Calculated MW 58kDa

location