Anti-ZW10 antibody

$300.00

  • Model: PAab09760
  • 50 Units in Stock
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Anti-ZW10 antibody

Product Name Anti-ZW10 antibody

Catalog No PAab09760

Packing 100ug

Form liquid

Alternative Name HZW10 antibody, KNTC1AP antibody, ZW10

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:15029241).

Immunogen ZW10, kinetochore associated, homolog (Drosophila)

Specificity Human

Tested Application ELISA,WB

Recommended dilution WB:1:500-1:5000;IP:1:200-1:2000

IHC use

WB use

Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09760( ZW10 Antibody) at dilution of 1:1000

Protein Information

Gene ID9183

Uniprot ID O43264

Calculated MW 90kDa

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