Anti-Zyxin antibody

$300.00

  • Model: PAab09764
  • 50 Units in Stock
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Anti-Zyxin antibody

Product Name Anti-Zyxin antibody

Catalog No PAab09764

Packing 100ug

Form liquid

Alternative Name ESP 2 antibody, HED 2 antibody, ZYX antibody, zyxin antibody, Zyxin 2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.

Immunogen zyxin

Specificity Human

Tested Application ELISA,WB

Recommended dilution WB:1:200-1:2000

IHC use

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09764(ZYX antibody) at dilution of 1:1000

Protein Information

Gene ID7791

Uniprot ID Q15942

Calculated MW 80kDa

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