NFATc2IP Antibody

$325.00

  • Model: ABF9128
  • 50 Units in Stock
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NFATc2IP Antibody

Catalog  ABF9128    Packing 100ug

Host Rabbit             Clonality  Polyclonal

Reactivity with Human

M.W.(Molecular Weight)  48kDa

Application  WB 

WB 1:1000

NFATc2IP Protein Information

Uniprot ID Q8NCF5

Function:

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity).

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